SCHEMBL16613165

SCHEMBL16613165

COC[SiH](CCCOCC1CO1)COC

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.55
ALDH1A1 P00352 4/20 0.51
TDP1 Q9NUW8 1/20 0.51
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701034 0.82 SMN1; SMN2 (0.63) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10071424 0.79 TSHR (0.74) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2623200 0.79 TSHR (0.82) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL233474 0.79 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4359009 0.78 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28250624 0.78 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10071427 0.77 TSHR (0.78) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2623199 0.77 TSHR (0.78) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10071426 0.77 TSHR (0.78) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28450397 0.77 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857436-B1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORP (JP) 2019-10-09 EP disclosed
US-9969843-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2018-05-15 US disclosed
US-9803052-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2017-10-31 US disclosed
US-20170051108-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-23 US disclosed
US-20170044314-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-16 US disclosed
US-9505879-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2016-11-29 US disclosed
US-20150133622-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2015-05-14 US disclosed
EP-2857436-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME Kaneka Corporation (JP) 2015-04-08 EP disclosed