Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517669 | 0.81 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28630771 | 0.78 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4810335 | 0.76 | TSHR (0.60) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1093578 | 0.76 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17880771 | 0.76 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4806192 | 0.75 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1796154 | 0.74 | SMN1; SMN2 (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL2623200 | 0.74 | TSHR (0.82) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10071424 | 0.74 | TSHR (0.74) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL3138135 | 0.74 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857436-B1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | KANEKA CORP (JP) | 2019-10-09 | — | — | EP | disclosed |
| US-9969843-B2 | Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same | KANEKA CORPORATION (JP) | 2018-05-15 | — | — | US | disclosed |
| US-9803052-B2 | Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same | KANEKA CORPORATION (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20170051108-A1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | KANEKA CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| US-20170044314-A1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | KANEKA CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |
| US-9505879-B2 | Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same | KANEKA CORPORATION (JP) | 2016-11-29 | — | — | US | disclosed |
| US-20150133622-A1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | KANEKA CORPORATION (JP) | 2015-05-14 | — | — | US | disclosed |
| EP-2857436-A1 | POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME | Kaneka Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |