SCHEMBL28630771

SCHEMBL28630771

COC(O)(CCCOCC1CO1)C([SiH3])(OC)OC

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517669 0.80 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL21773179 0.79 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16613166 0.78 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2597107 0.76 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4810335 0.75 TSHR (0.60) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1093578 0.75 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17880771 0.74 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4806192 0.73 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1796154 0.73 SMN1; SMN2 (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7920440 0.73 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117661776-A Negative-carbon environment-friendly multilayer reinforced raw soil-based prefabricated wallboard 扬州邗江中科南工建设工程与信息化研究中心 2024-03-08 CN claimed
CN-117185842-B Antifouling wear-resistant ceramic tile and preparation method thereof 广东方向陶瓷有限公司 2024-02-13 CN claimed
CN-117487308-A Reinforced halogen-free flame-retardant battery shell material and preparation method thereof 广东沃欧电子科技股份有限公司 2024-02-02 CN claimed
CN-117185842-A Antifouling wear-resistant ceramic tile and preparation method thereof 广东方向陶瓷有限公司 2023-12-08 CN claimed
CN-115672702-B Decorative board and processing technology thereof 青岛美中建材机械有限公司 2023-11-10 CN claimed
CN-117661776-A Negative-carbon environment-friendly multilayer reinforced raw soil-based prefabricated wallboard 扬州邗江中科南工建设工程与信息化研究中心 2024-03-08 CN disclosed
CN-117185842-B Antifouling wear-resistant ceramic tile and preparation method thereof 广东方向陶瓷有限公司 2024-02-13 CN disclosed
CN-117487308-A Reinforced halogen-free flame-retardant battery shell material and preparation method thereof 广东沃欧电子科技股份有限公司 2024-02-02 CN disclosed
CN-117185842-A Antifouling wear-resistant ceramic tile and preparation method thereof 广东方向陶瓷有限公司 2023-12-08 CN disclosed
CN-115672702-B Decorative board and processing technology thereof 青岛美中建材机械有限公司 2023-11-10 CN disclosed
CN-113384750-B Construction method of titanium alloy surface composite hydrogel coating for reducing bone tissue abrasion 上海交通大学 2022-08-12 CN disclosed
CN-113384750-A Construction method of titanium alloy surface composite hydrogel coating for reducing bone tissue abrasion 上海交通大学 2021-09-14 CN disclosed