Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 10/20 | 0.42 |
| ▸ | NPY1R | P25929 | 6/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661928 | 0.91 | CTSL (0.47) | NPY4RNPY1RNPY5RNPY2ROPRK1 | |
| SCHEMBL1662044 | 0.90 | NPY4R (0.38) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL17495217 | 0.87 | NPY4R (0.42) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL12792613 | 0.87 | NPY4R (0.54) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL12794620 | 0.87 | NPY4R (0.54) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL1661328 | 0.87 | NPY4R (0.37) | NPY4RNPY1RNPY5RNPY2RCTSL | |
| SCHEMBL19252729 | 0.84 | CTSL (0.47) | OPRK1CTSL | |
| SCHEMBL17518408 | 0.83 | NPY4R (0.46) | GRIA1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL1661064 | 0.83 | NPY4R (0.48) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13733975 | 0.80 | NPY4R (0.35) | KISS1RNPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |