Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | NPY2R | P49146 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252729 | 0.94 | CTSL (0.47) | CTSLCTSBCTSSCTSKSIRT2 | |
| SCHEMBL1661320 | 0.91 | GRIA1 (0.43) | CTSLNPY4ROPRK1NPY1RNPY2R | |
| SCHEMBL1661328 | 0.90 | NPY4R (0.37) | CTSLCTSBCTSSCTSKNPY4R | |
| SCHEMBL1662044 | 0.86 | NPY4R (0.38) | NPY4ROPRK1NPY1RNPY2RNPY5R | |
| SCHEMBL19252747 | 0.81 | PTGER4 (0.45) | CTSLNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17495217 | 0.81 | NPY4R (0.42) | NPY4ROPRK1NPY1RNPY2RNPY5R | |
| SCHEMBL1662059 | 0.79 | CTSL (0.54) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL1661064 | 0.79 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13733975 | 0.78 | NPY4R (0.35) | NPY4ROPRK1NPY1RNPY2RNPY5R | |
| SCHEMBL12794620 | 0.78 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |