SCHEMBL16613286

SCHEMBL16613286

c1ccc(-c2nc(-n3c4ccccc4c4c5ccccc5ccc43)nc3cocc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 6/20 0.40
HPGD P15428 4/20 0.40
NPSR1 Q6W5P4 3/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
LMNA P02545 2/20 0.38
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADORA2A P29274 2/20 0.32
NUDT1 P36639 1/20 0.32
KMT2A Q03164 3/20 0.32
CFTR P13569 1/20 0.32
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613288 0.98 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613387 0.93 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613304 0.91 MAPT (0.33) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613326 0.90 ENPP1 (0.36) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16785752 0.89 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613386 0.88 TUBB4A (0.32) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613303 0.88 FLT3 (0.31) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613396 0.87 KDM4E (0.48) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613287 0.87 ALDH1A1 (0.31) ALDH1A1KDM4EHPGDMAPTKMT2A
SCHEMBL31678 0.86 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed