SCHEMBL16613360

SCHEMBL16613360

c1ccc(-c2nc(-n3c4ccccc4c4c5ccccc5ccc43)nc3cscc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 6/20 0.39
HPGD P15428 4/20 0.39
NPSR1 Q6W5P4 3/20 0.39
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 2/20 0.37
NQO2 P16083 1/20 0.33
PTGER1 P34995 1/20 0.32
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADORA2A P29274 1/20 0.31
NUDT1 P36639 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613542 0.98 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613482 0.93 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613481 0.91 KDM4E (0.34) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613422 0.91 MAPT (0.32) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613543 0.90 FLT3 (0.32) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613455 0.88 NQO2 (0.31) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613362 0.88 TUBB4A (0.32) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16785752 0.88 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613344 0.88 KDM4E (0.47) ALDH1A1KDM4EHPGDNPSR1MAPT
SCHEMBL16613361 0.87 ALDH1A1 (0.32) ALDH1A1KDM4EHPGDMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed