SCHEMBL16613398

SCHEMBL16613398

c1ccc(-c2cc(-c3ccccc3)cc(-c3nc(-n4c5ccccc5c5c6ccccc6ccc54)nc4ccoc34)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
MAPT P10636 2/20 0.32
RORC P51449 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.30
LMNA P02545 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAPK3 P27361 1/20 0.30
AHR P35869 1/20 0.30
PAX8 Q06710 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613306 0.94 ALDH1A1 (0.35) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613305 0.93 HPGD (0.36) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613665 0.89 PIK3CA (0.39) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613307 0.89 BRD4 (0.34) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613376 0.89 PIK3CD (0.32) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613375 0.87 KDM4E (0.32) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613489 0.85 CYP1A1 (0.30) CYP1A1CYP1A2FYNMAPK3AHR
SCHEMBL16613387 0.84 ALDH1A1 (0.34) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16613374 0.84 PIK3CD (0.31) PIK3CDPIK3CAKDM4EALDH1A1HPGD
SCHEMBL16613743 0.83 PIK3CA (0.38) PIK3CDPIK3CAKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed