SCHEMBL16613665

SCHEMBL16613665

c1ccc(-c2cc(-c3ccccc3)cc(-c3nc(-n4c5ccccc5c5ccccc54)nc4ccoc34)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.39
PIK3CD O00329 2/20 0.39
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 6/20 0.37
HPGD P15428 5/20 0.37
NPSR1 Q6W5P4 5/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 3/20 0.35
LMNA P02545 3/20 0.35
RORC P51449 1/20 0.33
ATM Q13315 1/20 0.33
PIK3R1 P27986 1/20 0.32
KMT2A Q03164 3/20 0.30
MEN1 O00255 2/20 0.30
POLB P06746 2/20 0.30
GAA P10253 2/20 0.30
NPC1 O15118 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613743 0.94 PIK3CA (0.38) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613671 0.92 HPGD (0.41) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613768 0.92 HPGD (0.43) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613401 0.90 KDM4E (0.38) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613398 0.89 PIK3CD (0.34) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613500 0.85 KDM4E (0.38) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613471 0.85 KDM4E (0.39) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613611 0.85 ALDH1A1 (0.37) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613613 0.85 ALDH1A1 (0.37) PIK3CAPIK3CDALDH1A1KDM4EHPGD
SCHEMBL16613612 0.84 PIK3CA (0.35) PIK3CAPIK3CDALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed