SCHEMBL16613470

SCHEMBL16613470

c1ccc(-c2nc(-n3c4ccccc4c4c5ccccc5ccc43)nc3ccoc23)nc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.38
AHR P35869 1/20 0.36
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP1B1 Q16678 1/20 0.34
NPC1 O15118 4/20 0.33
KDM4E B2RXH2 3/20 0.33
TP53 P04637 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
TGFBR1 P36897 2/20 0.32
RAB9A P51151 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
METAP1 P53582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613769 0.89 MCL1 (0.43) MCL1NPC1KDM4ETP53SMN1; SMN2
SCHEMBL16613578 0.85 AHR (0.36) MCL1AHRCYP1A1CYP1A2CYP1B1
SCHEMBL16613305 0.84 HPGD (0.36) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL16613351 0.84 AHR (0.37) MCL1AHRCYP1A1CYP1A2CYP1B1
SCHEMBL16613374 0.84 PIK3CD (0.31) KDM4ETP53SMN1; SMN2ALDH1A1MAPT
SCHEMBL16613306 0.83 ALDH1A1 (0.35) NPC1KDM4EALDH1A1MAPTHPGD
SCHEMBL16613389 0.82 PIK3CD (0.30) PIK3CDPIK3CA
SCHEMBL16613655 0.81 MCL1 (0.36) MCL1AHRNPC1KDM4ETP53
SCHEMBL16613398 0.81 PIK3CD (0.34) AHRCYP1A1CYP1A2KDM4EALDH1A1
SCHEMBL16613375 0.81 KDM4E (0.32) KDM4ETP53SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed