SCHEMBL16613703

SCHEMBL16613703

c1ccc(-c2nc(-n3c4ccccc4c4c5ccccc5ccc43)nc3sccc23)nc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KRAS P01116 1/20 0.39
AHR P35869 1/20 0.36
ADORA1 P30542 5/20 0.35
TGFBR1 P36897 1/20 0.34
ADORA2A P29274 3/20 0.34
MCL1 Q07820 3/20 0.34
VCP P55072 1/20 0.32
MAPK10 P53779 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
OPRK1 P41145 1/20 0.32
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613460 0.89 KRAS (0.45) KRASADORA1TGFBR1ADORA2AMCL1
SCHEMBL16613469 0.84 VCP (0.36) ADORA2AVCPKDM4EALDH1A1MAPT
SCHEMBL16613625 0.84 VCP (0.34) VCPALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL16613713 0.83 DHODH (0.36) ADORA2AVCPKDM4EALDH1A1MAPT
SCHEMBL16613715 0.82 VCP (0.33) VCP
SCHEMBL16613714 0.81 VCP (0.34) ADORA2AVCPKDM4EALDH1A1MAPT
SCHEMBL16613555 0.81 DHODH (0.34) AHRADORA2AVCP
SCHEMBL16613655 0.81 MCL1 (0.36) AHRTGFBR1MCL1KDM4ENPC1
SCHEMBL16613628 0.81 ADORA2A (0.41) ADORA2AVCP
SCHEMBL16613702 0.80 VCP (0.32) VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed