Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618700 | 0.85 | PKM (0.60) | PKMSLC6A2SLC6A4LMNASMN1; SMN2 | |
| SCHEMBL8156311 | 0.83 | PKM (0.52) | PKMSLC6A2SLC6A4LMNASMN1; SMN2 | |
| SCHEMBL6184463 | 0.83 | PKM (0.54) | PKMSLC6A2SLC6A4LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8153630 | 0.82 | PKM (0.51) | PKMSLC6A2SLC6A4LMNASMN1; SMN2 | |
| SCHEMBL6793306 | 0.81 | PKM (0.49) | PKMSLC6A2SLC6A4LMNASMN1; SMN2 | |
| SCHEMBL1617124 | 0.74 | PKM (0.55) | PKMLMNASMN1; SMN2ALDH1A1MCOLN3 | |
| SCHEMBL6301308 | 0.74 | PKM (0.45) | PKMHTR6 | |
| SCHEMBL1617222 | 0.72 | HDAC3 (0.50) | PKMLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22089254 | 0.71 | TSHR (0.47) | SLC6A2SLC6A4LMNAALDH1A1TSHR | |
| SCHEMBL20869728 | 0.71 | PKM (0.63) | PKMLMNASMN1; SMN2ALDH1A1MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088754-A1 | SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | EMELEN KRISTOF VAN (BE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088754-A1 | SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | HDAC3, HDAC1, HDAC11 | PKM 424/4885SLC6A2 3795/4885SLC6A4 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.