Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 19/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600438 | 0.89 | ENPP2 (0.67) | ENPP2 | |
| SCHEMBL16614227 | 0.86 | ENPP2 (0.61) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16614252 | 0.82 | ENPP2 (0.56) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600529 | 0.74 | ENPP2 (0.78) | ENPP2 | |
| SCHEMBL16600403 | 0.73 | ENPP2 (0.69) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600401 | 0.73 | ENPP2 (0.69) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600404 | 0.73 | ENPP2 (0.81) | ENPP2 | |
| SCHEMBL16600195 | 0.73 | ENPP2 (0.75) | ENPP2 | |
| SCHEMBL17940583 | 0.72 | ENPP2 (0.70) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600455 | 0.72 | ENPP2 (0.67) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |