Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600489 | 0.87 | ENPP2 (0.72) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16614227 | 0.87 | ENPP2 (0.61) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16614209 | 0.82 | ENPP2 (0.53) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600604 | 0.82 | ENPP2 (0.71) | ENPP2 | |
| SCHEMBL16600335 | 0.77 | ENPP2 (0.80) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600297 | 0.76 | ENPP2 (0.79) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL19750133 | 0.75 | ENPP2 (0.73) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600682 | 0.75 | ENPP2 (0.72) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600425 | 0.74 | ENPP2 (0.76) | ENPP2AKR1B1PTGDR2 | |
| SCHEMBL16600529 | 0.74 | ENPP2 (0.78) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |