SCHEMBL16614435

SCHEMBL16614435

Cc1ccc(N(c2ccc(-c3ncccn3)cc2)c2ccc(-c3ncncn3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 1/20 0.41
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
ADRB2 P07550 2/20 0.37
CYP2A6 P11509 1/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 3/20 0.35
TP53 P04637 2/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 6/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21018825 0.91 CLK4 (0.47) CLK4MEN1KMT2AADRB2CYP2A6
SCHEMBL21018826 0.89 SMN1; SMN2 (0.46) MEN1KMT2ANPC1RAB9ATP53
SCHEMBL16614455 0.89 NPC1 (0.41) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL16614434 0.87 SMN1; SMN2 (0.47) CLK4MEN1KMT2AADRB2CYP2A6
SCHEMBL21012485 0.86 ALDH1A1 (0.39) CLK4MEN1KMT2AADRB2CYP2A6
SCHEMBL21019138 0.85 NPC1 (0.44) CLK4MEN1KMT2AADRB2NPC1
SCHEMBL18909522 0.85 CLK4 (0.42) CLK4MEN1KMT2AADRB2NPC1
SCHEMBL3119508 0.82 NPC1 (0.41) CLK4MEN1KMT2ANPC1RAB9A
SCHEMBL21019111 0.81 CLK4 (0.44) CLK4MEN1KMT2AADRB2CYP2A6
SCHEMBL28416187 0.80 ALDH1A1 (0.43) CLK4MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015046982-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed