Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 5/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615492 | 0.77 | ALDH1A1 (0.76) | RAB9ANPC1KMT2AMAPTTSHR | |
| SCHEMBL17947664 | 0.76 | ALDH1A1 (0.66) | RAB9ANPC1KMT2AMAPTTSHR | |
| SCHEMBL6848423 | 0.74 | RAB9A (0.84) | RAB9ANPC1KMT2AMAPTTSHR | |
| SCHEMBL8768779 | 0.74 | RAB9A (0.82) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL108116 | 0.74 | NPC1 (1.00) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12111900 | 0.73 | RAB9A (0.76) | RAB9ANPC1KMT2AMAPTTSHR | |
| SCHEMBL4727186 | 0.73 | RAB9A (0.81) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28925954 | 0.72 | RAB9A (0.85) | RAB9ANPC1KMT2AMAPTTSHR | |
| SCHEMBL2971586 | 0.72 | RAB9A (0.78) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11238457 | 0.71 | RAB9A (1.00) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042685-A1 | INHIBITORS OF POLYNUCLEOTIDE REPEAT-ASSOCIATED RNA FOCI AND USES THEREOF | VALORISATION-RECHERCHE (CA) | 2015-04-02 | — | — | WO | disclosed |