SCHEMBL16615743

CC(O)[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N(C)[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)O)CCCCNC(=O)CC[C@H](NC(=O)[C@@H](N)CO)C(=O)N1C

nearest known ligand 0.42

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	TERF2	Q15554	4/20	0.42

▸	SRC	P12931	1/20	0.40

▸	OPRM1	P35372	2/20	0.40

▸	OPRD1	P41143	2/20	0.40

▸	OPRK1	P41145	2/20	0.40

▸	MC1R	Q01726	1/20	0.39

▸	SSTR2	P30874	1/20	0.38

▸	SSTR4	P31391	1/20	0.38

▸	SSTR5	P35346	1/20	0.38

▸	SSTR1	P30872	2/20	0.38

▸	SSTR3	P32745	1/20	0.38

▸	BIRC3	Q13489	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16615917	0.93	TERF2 (0.41)	TERF2SRCBIRC3
SCHEMBL16615886	0.88	SRC (0.40)	TERF2SRCBIRC3
SCHEMBL16615750	0.87	SRC (0.47)	TERF2SRCOPRM1OPRD1OPRK1
SCHEMBL16615868	0.86	MC1R (0.45)	SRCOPRM1OPRD1OPRK1MC1R
SCHEMBL16615764	0.85	MC1R (0.46)	TERF2SRCOPRM1OPRD1OPRK1
SCHEMBL16615899	0.83	SIRT2 (0.39)	OPRM1OPRD1OPRK1MC1R
SCHEMBL16615888	0.82	MC1R (0.38)	SRCOPRM1OPRD1OPRK1MC1R
SCHEMBL16615890	0.81	SRC (0.39)	SRCOPRM1OPRD1OPRK1MC1R
SCHEMBL16615891	0.80	SSTR1 (0.36)	SRCOPRM1OPRD1OPRK1MC1R
SCHEMBL16615762	0.79	SRC (0.43)	TERF2SRCSSTR2SSTR4SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015044900-A1	THERAPEUTIC IMMUNOMODULATING COMPOUNDS	AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN)	2015-04-02	—	—	WO	disclosed