Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615896 | 0.83 | MMP1 (0.41) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615623 | 0.83 | SIRT2 (0.42) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615898 | 0.82 | MMP1 (0.39) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615761 | 0.79 | MMP1 (0.41) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615594 | 0.78 | MC1R (0.46) | MMP1MMP9KDM1ARCOR1MMP2 | |
| SCHEMBL16615855 | 0.77 | MC1R (0.43) | MMP1MMP9KDM1ARCOR1MMP2 | |
| SCHEMBL16615904 | 0.74 | SRC (0.48) | MMP1MMP9KDM1ARCOR1MMP2 | |
| SCHEMBL16615622 | 0.73 | MMP1 (0.41) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615899 | 0.73 | SIRT2 (0.39) | SIRT2SIRT1SIRT3MMP1MMP9 | |
| SCHEMBL16615873 | 0.72 | KEAP1 (0.42) | SIRT2SIRT1SIRT3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044900-A1 | THERAPEUTIC IMMUNOMODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-04-02 | — | — | WO | disclosed |