SCHEMBL16616016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16616165	0.86	CNR1 (0.51)	MCL1BAK1CNR2CNR1MEN1
	SCHEMBL16616758	0.78	MCL1 (0.55)	MCL1BAK1FOLH1MEN1KMT2A
	SCHEMBL16616128	0.76	MCL1 (0.50)	MCL1BAK1CNR1FOLH1MEN1
	SCHEMBL12076414	0.75	CTSV (0.51)	MCL1BAK1FOLH1MRGPRX4MEN1
	SCHEMBL16616669	0.74	MCL1 (0.48)	MCL1BAK1CNR1FOLH1MEN1
	SCHEMBL31159061	0.72	MCL1 (0.64)	MCL1BAK1FOLH1MEN1KMT2A
	SCHEMBL31727623	0.72	MCL1 (0.64)	MCL1BAK1FOLH1MEN1KMT2A
	SCHEMBL21331681	0.71	MCL1 (0.59)	MCL1BAK1CNR1FOLH1MEN1
	SCHEMBL17674483	0.70	PIN1 (0.59)	MCL1BAK1CNR1FOLH1MEN1
	SCHEMBL18584645	0.70	FOLH1 (0.49)	MCL1BAK1FOLH1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.