SCHEMBL16616526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16616528	1.00	DHODH (0.49)	DHODHTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL16616471	0.91	TUBB1 (0.48)	TUBB1ABCG2ABCB1SMN1; SMN2MEN1
	SCHEMBL16616524	0.91	ALDH1A1 (0.55)	TUBB1ABCG2ABCB1MEN1MAPT
	SCHEMBL16616467	0.91	TUBB1 (0.48)	TUBB1ABCG2ABCB1SMN1; SMN2MEN1
	SCHEMBL16616525	0.91	ALDH1A1 (0.55)	TUBB1ABCG2ABCB1MEN1MAPT
	SCHEMBL16616734	0.91	TUBB1 (0.50)	DHODHTUBB1ABCG2ABCB1SMN1; SMN2
	SCHEMBL16616624	0.91	SMN1; SMN2 (0.56)	DHODHTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL16616733	0.91	TUBB1 (0.50)	DHODHTUBB1ABCG2ABCB1SMN1; SMN2
	SCHEMBL16616625	0.91	SMN1; SMN2 (0.56)	DHODHTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL16616473	0.91	RAB9A (0.49)	DHODHTUBB1ABCG2ABCB1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.