Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962421 | 0.88 | — | — | |
| SCHEMBL15922574 | 0.83 | — | — | |
| SCHEMBL22414 | 0.76 | — | — | |
| Formic Acid SCHEMBL19466598 | 0.75 | APLNR (0.35) | APLNR | |
| SCHEMBL3185201 | 0.74 | SLC6A1 (0.39) | APLNR | |
| SCHEMBL29224201 | 0.74 | SLC6A1 (0.39) | APLNR | |
| SCHEMBL20548690 | 0.73 | — | — | |
| SCHEMBL493211 | 0.73 | FFAR4 (0.34) | — | |
| SCHEMBL8040596 | 0.73 | APLNR (0.41) | APLNR | |
| SCHEMBL16911630 | 0.73 | APLNR (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |