Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16617488 | 1.00 | CYP3A4 (0.47) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL9112690 | 0.77 | CYP3A4 (0.50) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL6553874 | 0.77 | NQO2 (0.44) | ABCG2TUBB1NQO2CYP1A1CYP1B1 | |
| SCHEMBL6553870 | 0.77 | NQO2 (0.44) | ABCG2TUBB1NQO2CYP1A1CYP1B1 | |
| SCHEMBL9112687 | 0.77 | CYP3A4 (0.50) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL16723081 | 0.74 | CYP3A4 (0.44) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL16715104 | 0.74 | CYP3A4 (0.44) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL16715103 | 0.74 | CYP3A4 (0.44) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL28015177 | 0.71 | CYP3A4 (0.41) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL16389267 | 0.71 | CYP3A4 (0.57) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593060-B2 | Compounds for enhancing generation of chemical species | TOYO GOSEI CO., LTD (JP) | 2017-03-14 | — | — | US | disclosed |
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20150140493-A1 | COMPOUNDERS FOR ENHANCING GENERATION OF CHEMICAL SPECIES | TOYO GOSEI CO., LTD (JP) | 2015-05-21 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | PPOX, CYBB, CBR3 | CYP3A4 520/4885USP2 2279/4885MAPK1 2552/4885 |
| US-20150140493-A1 | COMPOUNDERS FOR ENHANCING GENERATION OF CHEMICAL SPECIES | GFER, MEP1A, PPOX | CYP3A4 843/4885USP2 2667/4885MAPK1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.