Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328597 | 1.00 | SIRT6 (0.44) | SIRT6SIRT1PAOXGSRRNPEP | |
| SCHEMBL28158999 | 0.94 | SIRT6 (0.39) | SIRT6SIRT1PAOXGSRRNPEP | |
| SCHEMBL28335157 | 0.83 | GSR (0.44) | SIRT6SIRT1GSRRNPEPCPB2 | |
| SCHEMBL27849229 | 0.82 | DPP8 (0.37) | SIRT6SIRT1PAOXGSRRNPEP | |
| SCHEMBL109296 | 0.81 | PLA2G2C (0.45) | SIRT6SIRT1CA2 | |
| SCHEMBL5494838 | 0.81 | GSR (0.38) | SIRT6SIRT1GSRRNPEPCPB2 | |
| SCHEMBL5155641 | 0.81 | GSR (0.38) | SIRT6SIRT1GSRRNPEPCPB2 | |
| SCHEMBL1649294 | 0.81 | PLA2G2C (0.44) | SIRT6SIRT1CA1CA2DPP8 | |
| SCHEMBL4323327 | 0.81 | PLA2G2C (0.44) | SIRT6SIRT1CA1CA2DPP8 | |
| SCHEMBL9115885 | 0.81 | DPP7 (0.41) | SIRT6SIRT1GSRRNPEPCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390731-A | Combined cancer therapy with pentaaza macrocyclic complexes and hormonal therapeutic agents | 加莱拉实验室有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-2483398-A2 | ACETYL LYSINE INCORPORATION WITH tRNA SYNTHETASE | Medical Research Council (United Kingdom) (GB) | 2012-08-08 | — | — | EP | disclosed |
| US-20120190825-A1 | ACETYL LYSINE INCORPORATION WITH tRNA SYNTHETASE | MEDICAL RESEARCH COUNCIL (GB) | 2012-07-26 | — | — | US | disclosed |
| WO-2011039519-A2 | ACETYL LYSINE INCORPORATION WITH tRNA SYNTHETASE | MEDICAL RESEARCH COUNCIL (UNITED KINGDOM) (GB) | 2011-04-07 | — | — | WO | disclosed |