SCHEMBL5155641

SCHEMBL5155641

NCCCC[C@@H]([C]=O)NC(=O)CN

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.38
CTSC P53634 2/20 0.37
RNPEP Q9H4A4 1/20 0.37
FOLH1 Q04609 1/20 0.37
SLC15A2 Q16348 1/20 0.35
CPB2 Q96IY4 4/20 0.34
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
SLC6A5 Q9Y345 1/20 0.32
SIRT6 Q8N6T7 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
NMT2 O60551 1/20 0.30
NMT1 P30419 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494838 1.00 GSR (0.38) GSRCTSCRNPEPFOLH1SLC15A2
SCHEMBL2182070 0.87 SLC6A5 (0.40) GSRRNPEPFOLH1CPB2SLC6A5
SCHEMBL27898255 0.87 F2 (0.38) GSRCTSCRNPEPFOLH1SLC6A5
SCHEMBL10422593 0.86 NMT2 (0.33) GSRRNPEPFOLH1SLC15A2DPP8
SCHEMBL29198588 0.86 FOLH1 (0.41) GSRRNPEPFOLH1CPB2DPP8
SCHEMBL27535723 0.86 SLC6A5 (0.45) GSRFOLH1CPB2SLC6A5CYP2D6
SCHEMBL3717425 0.86 SLC6A5 (0.45) GSRFOLH1CPB2SLC6A5CYP2D6
SCHEMBL27849229 0.86 DPP8 (0.37) GSRRNPEPFOLH1CPB2DPP8
SCHEMBL10701105 0.84 CTSC (0.36) CTSC
SCHEMBL28335157 0.83 GSR (0.44) GSRRNPEPFOLH1CPB2DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070093425-A1 Vitamin c derivatives with peptide, preparation method thereof and composition comprising the same PEPTRON CO., LTD. (KR) 2007-04-26 US claimed
US-20060160989-A1 Polypeptide useful as antiallergic/antiasthmatic activity, methods for the preparation thereof, pharmaceutical compositions containing such polypeptide and use thereof COUNCIL OF SCIENTIC AND INDUSTRIAL RESEARCH (IN) 2006-07-20 US claimed
EP-1348714-A1 Polypeptide useful as anti-allergic/antiasthmatic, methods for the preparation thereof and pharmaceutical compositions containing such polypeptide and their use COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-01 EP claimed
US-4980343-A Inhibit colon and rectal tumors BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 US claimed
EP-0365956-A2 Carcinostatic agents BAYER AG (DE) 1990-05-02 EP claimed
US-20240060991-A1 METHODS OF IDENTIFYING THE PRESENCE AND/OR CONCENTRATION AND/OR AMOUNT OF PROTEINS OR PROTEOMES PROTEOTYPE DIAGNOSTICS LTD. (GB) 2024-02-22 US disclosed
CN-117203527-A Method for identifying the presence and/or concentration and/or amount of a protein or group of proteins 蛋白类型诊断公司 2023-12-08 CN disclosed
EP-4196797-A1 METHODS OF IDENTIFYING THE PRESENCE AND/OR CONCENTRATION AND/OR AMOUNT OF PROTEINS OR PROTEOMES Proteotype Diagnostics Ltd (GB) 2023-06-21 EP disclosed
WO-2022034336-A1 METHODS OF IDENTIFYING THE PRESENCE AND/OR CONCENTRATION AND/OR AMOUNT OF PROTEINS OR PROTEOMES Proteotype Diagnostics Ltd (GB) 2022-02-17 WO disclosed
US-20150111246-A1 SITE-SPECIFIC ENZYMATIC MODIFICATION OF EXENDINS AND ANALOGS THEREOF ASTRAZENECA PHARMACEUTICALS LP 2015-04-23 US disclosed
EP-1348714-B1 Polypeptide useful as anti-allergic/antiasthmatic, methods for the preparation thereof and pharmaceutical compositions containing such polypeptide and their use COUNCIL SCIENT IND RES (IN) 2007-01-03 EP disclosed
US-20060160989-A1 Polypeptide useful as antiallergic/antiasthmatic activity, methods for the preparation thereof, pharmaceutical compositions containing such polypeptide and use thereof COUNCIL OF SCIENTIC AND INDUSTRIAL RESEARCH (IN) 2006-07-20 US disclosed
EP-1348714-A1 Polypeptide useful as anti-allergic/antiasthmatic, methods for the preparation thereof and pharmaceutical compositions containing such polypeptide and their use COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-01 EP disclosed
US-4980343-A Inhibit colon and rectal tumors BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 US disclosed
EP-0365956-A2 Carcinostatic agents BAYER AG (DE) 1990-05-02 EP disclosed
EP-0010297-B1 DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1983-04-13 EP disclosed
US-4272525-A FUNGICIDES SCHERING CORPORATION (US) 1981-06-09 US disclosed
EP-0010297-A1 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1980-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160989-A1 Polypeptide useful as antiallergic/antiasthmatic activity, methods for the preparation thereof, pharmaceutical compositions containing such polypeptide and use thereof NGLY1, ARGLU1, ARG1 GSR 3918/4885CTSC 100/4885RNPEP 94/4885
US-20070093425-A1 Vitamin c derivatives with peptide, preparation method thereof and composition comprising the same PROC, CTRC, GC GSR 1879/4885CTSC 36/4885RNPEP 35/4885
US-20150111246-A1 SITE-SPECIFIC ENZYMATIC MODIFICATION OF EXENDINS AND ANALOGS THEREOF ENPEP, PEPD, DNPEP GSR 1460/4885CTSC 48/4885RNPEP 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.