Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.38 |
| ▸ | TDO2 | P48775 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840417 | 0.77 | IDO1 (0.38) | IDO1TDO2DPP4ACP3 | |
| SCHEMBL20588883 | 0.77 | RIPK1 (0.36) | DPP4TSHRF2 | |
| SCHEMBL10654262 | 0.76 | IDO1 (0.48) | IDO1TDO2TSHR | |
| SCHEMBL1307241 | 0.73 | DPP4 (0.44) | IDO1TDO2DPP4F2 | |
| SCHEMBL2061580 | 0.73 | LMNA (0.38) | IDO1TDO2TSHRACP3 | |
| SCHEMBL7636381 | 0.73 | TSHR (0.44) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL7851156 | 0.73 | TACR1 (0.39) | IDO1TDO2 | |
| SCHEMBL5196720 | 0.73 | IDO1 (0.38) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL518806 | 0.73 | IDO1 (0.38) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL19305465 | 0.72 | MIF (0.34) | DPP4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3051946-A1 | USE OF SUBSTITUTED DIHYDRO-OXINDOLYL SULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-10 | — | — | EP | claimed |
| WO-2015049351-A1 | USE OF SUBSTITUTED DIHYDRO-OXINDOLYL SULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS | BAYER CROPSCIENCE AG (DE) | 2015-04-09 | — | — | WO | claimed |