Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618844 | 0.87 | NFE2L2 (0.56) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL9431977 | 0.84 | NFE2L2 (0.52) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL2187122 | 0.83 | ALDH1A1 (0.37) | NFE2L2NPC1CHRM5RELAACHE | |
| SCHEMBL23457236 | 0.82 | NFE2L2 (0.60) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL16167415 | 0.81 | NFE2L2 (0.65) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL256055 | 0.81 | NFE2L2 (0.65) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL1759603 | 0.80 | NFE2L2 (0.58) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL16950982 | 0.79 | NFE2L2 (0.52) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL16955931 | 0.79 | NFE2L2 (0.47) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL27617456 | 0.78 | NFE2L2 (0.56) | NFE2L2CYP1A2CYP3A4CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | claimed |
| CN-102633727-A | Synthetic method of 2-methylthio-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-5-methyl carbonate | UNIV ZHEJIANG TECHNOLOGY | 2012-08-15 | — | — | CN | claimed |
| CN-102026980-A | Isoquinolinone derivatives as NK3 antagonists | LUNDBECK & CO AS H | 2011-04-20 | — | — | CN | claimed |
| CN-101679271-A | Quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of central nervous system and peripheral diseases | ASTRAZENECA AB | 2010-03-24 | — | — | CN | claimed |
| CN-101679276-A | Isoquinolinone derivatives as nk3 antagonists | LUNDBECK & CO AS H | 2010-03-24 | — | — | CN | claimed |
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | claimed |
| CN-101370782-A | Alkylsulphonamide quinolines | ASTRAZENECA AB (SE) | 2009-02-18 | — | — | CN | claimed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-110358445-B | Composition for forming water-repellent film and water-repellent film | 信越化学工业株式会社 | 2022-06-17 | — | — | CN | disclosed |
| US-11118072-B2 | Water repellent film-forming composition and water repellent film | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| EP-3553121-B1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-102026980-A | Isoquinolinone derivatives as NK3 antagonists | LUNDBECK & CO AS H | 2011-04-20 | — | — | CN | disclosed |
| CN-101679276-A | Isoquinolinone derivatives as nk3 antagonists | LUNDBECK & CO AS H | 2010-03-24 | — | — | CN | disclosed |
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| CN-101370782-A | Alkylsulphonamide quinolines | ASTRAZENECA AB (SE) | 2009-02-18 | — | — | CN | disclosed |
| CN-100417636-C | Optically active 1-(fluoro-, trifluoromethyl-or trifluoromethoxy-substituted phenyl) alkylamine n-monoalkyl derivatives and process for producing same | CENTRAL GLASS CO LTD (JP) | 2008-09-10 | — | — | CN | disclosed |
| CN-101128421-A | Methods and compositions for treating amyloid-related diseases | NEUROCHEM INTERNAT LTD (CH) | 2008-02-20 | — | — | CN | disclosed |
| CN-1671647-A | Optically active 1-(fluoro-, trifluoromethyl-or trifluoromethoxy-substituted phenyl) alkylamine n-monoalkyl derivatives and process for producing same | CENTRAL GLASS CO LTD (JP) | 2005-09-21 | — | — | CN | disclosed |