Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18982074 | 0.86 | MEN1 (0.49) | MAPTALDH1A1TDP1KMT2APOLB | |
| SCHEMBL28676925 | 0.86 | MAPT (0.49) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL3117835 | 0.86 | ALDH1A1 (0.69) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL7948673 | 0.84 | MAPT (0.53) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL9445187 | 0.83 | MAPT (0.54) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL17353527 | 0.80 | CYP1A2 (0.53) | MAPTALDH1A1TDP1POLBGAA | |
| SCHEMBL18982479 | 0.80 | CYP1A2 (0.53) | MAPTALDH1A1TDP1POLBGAA | |
| SCHEMBL25565309 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL17630097 | 0.78 | MAPT (0.49) | MAPTALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL15054397 | 0.78 | KDM4E (0.46) | MAPTALDH1A1TDP1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |