Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117835 | 0.86 | ALDH1A1 (0.69) | MAPTALDH1A1TDP1KDM4ECYP4F2 | |
| SCHEMBL16618859 | 0.84 | MAPT (0.53) | MAPTALDH1A1TDP1KDM4ECYP4F2 | |
| SCHEMBL9445187 | 0.83 | MAPT (0.54) | MAPTALDH1A1TDP1KDM4ECYP4F2 | |
| SCHEMBL2130827 | 0.80 | CYP4F2 (0.53) | MAPTALDH1A1KDM4ECYP3A4CYP4F2 | |
| SCHEMBL17806642 | 0.80 | CYP4F2 (0.53) | MAPTALDH1A1KDM4ECYP3A4CYP4F2 | |
| SCHEMBL14436163 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1TDP1KDM4ECYP3A4 | |
| SCHEMBL7403134 | 0.80 | TDP1 (0.54) | MAPTALDH1A1TDP1KDM4ECYP3A4 | |
| SCHEMBL1771537 | 0.78 | CYP3A4 (0.56) | MAPTALDH1A1TDP1KDM4ECYP3A4 | |
| SCHEMBL30873107 | 0.78 | CYP3A4 (0.56) | MAPTALDH1A1TDP1KDM4ECYP3A4 | |
| SCHEMBL588348 | 0.78 | CYP3A4 (0.63) | MAPTALDH1A1TDP1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002802-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |