Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980663 | 0.86 | ALDH1A1 (0.49) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL18249984 | 0.83 | HSD17B10 (0.46) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL18258249 | 0.83 | ALDH1A1 (0.44) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL18249936 | 0.82 | ALDH1A1 (0.46) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL1903461 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL17467704 | 0.80 | AKR1C3 (0.41) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL19551776 | 0.79 | BRD4 (0.51) | ERN1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29718836 | 0.79 | BRD4 (0.51) | ERN1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24398702 | 0.78 | MEN1 (0.46) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL29619095 | 0.78 | MEN1 (0.46) | TDP1ERN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |