Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980663 | 0.86 | ALDH1A1 (0.49) | ALDH1A1ERN1MEN1POLBKMT2A | |
| SCHEMBL18249984 | 0.83 | HSD17B10 (0.46) | ALDH1A1FFAR1ERN1MEN1POLB | |
| SCHEMBL16618869 | 0.83 | TDP1 (0.48) | ALDH1A1ERN1MEN1POLBKMT2A | |
| SCHEMBL18249936 | 0.82 | ALDH1A1 (0.46) | ALDH1A1ERN1MEN1POLBKMT2A | |
| SCHEMBL1903461 | 0.81 | TDP1 (0.48) | ALDH1A1FFAR1POLBTDP1BRD4 | |
| SCHEMBL17467704 | 0.80 | AKR1C3 (0.41) | ALDH1A1ERN1MEN1POLBKMT2A | |
| SCHEMBL26092466 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HIF1AKMT2ATSHRTDP1 | |
| SCHEMBL13036090 | 0.77 | NPC1 (0.47) | FFAR1ERN1POLBBRD4NPC1 | |
| SCHEMBL19551776 | 0.76 | BRD4 (0.51) | ALDH1A1ERN1MEN1KMT2AEDNRA | |
| SCHEMBL29718836 | 0.76 | BRD4 (0.51) | ALDH1A1ERN1MEN1KMT2AEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016186453-A1 | QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS | KAINOS MEDICINE, INC. (KR) | 2016-11-24 | — | — | WO | disclosed |