Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.49 |
| ▸ | BRD2 | P25440 | 6/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CCL2 | P13500 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | TAF1 | P21675 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619839 | 0.91 | BRD4 (0.59) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL11909184 | 0.91 | BRD4 (0.59) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL11980666 | 0.85 | LMNA (0.48) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619324 | 0.85 | CYP3A4 (0.48) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16618852 | 0.80 | EGFR (0.42) | — | |
| SCHEMBL16618856 | 0.80 | EGFR (0.42) | — | |
| SCHEMBL18249908 | 0.80 | BRD4 (0.56) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL13732483 | 0.80 | BRD4 (0.56) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL12096364 | 0.80 | BRD4 (0.62) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL1907655 | 0.80 | BRD4 (0.62) | BRD4BRD2BRD3BRDTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |