Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618824 | 0.86 | S1PR4 (0.35) | S1PR4EGFRERBB2NPC1RECQL | |
| SCHEMBL18114309 | 0.82 | PDGFRB (0.43) | EGFR | |
| SCHEMBL29744240 | 0.79 | PDGFRB (0.49) | EGFRERBB2 | |
| SCHEMBL246700 | 0.79 | PDGFRB (0.49) | EGFRERBB2 | |
| SCHEMBL28826672 | 0.78 | ENPP1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL26102510 | 0.77 | PDGFRB (0.48) | EGFRERBB2 | |
| SCHEMBL21050767 | 0.77 | MAPT (0.37) | EGFRVCAM1 | |
| SCHEMBL16618812 | 0.76 | EGFR (0.39) | EGFRERBB2 | |
| SCHEMBL16618815 | 0.76 | EGFR (0.39) | EGFRERBB2 | |
| SCHEMBL29969235 | 0.75 | CYP1A2 (0.37) | EGFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |