Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15973592 | 0.87 | PDGFRB (0.40) | MAPTEGFRKDM4E | |
| SCHEMBL16619181 | 0.86 | S1PR4 (0.40) | S1PR4EGFRERBB2NPC1RECQL | |
| SCHEMBL16619235 | 0.83 | CTSB (0.32) | — | |
| SCHEMBL29970057 | 0.82 | PDGFRB (0.43) | ALDH1A1MAPTEGFRKDM4E | |
| SCHEMBL26131542 | 0.82 | PDGFRB (0.43) | ALDH1A1MAPTEGFRKDM4E | |
| SCHEMBL16618814 | 0.81 | CTSB (0.33) | ALDH1A1MAPTEGFRERBB2RAB9A | |
| SCHEMBL21358581 | 0.79 | PDGFRA (0.49) | ALDH1A1MAPTEGFRERBB2KDM4E | |
| SCHEMBL16618826 | 0.77 | CYP1A2 (0.41) | ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL28949882 | 0.77 | PDGFRB (0.41) | — | |
| SCHEMBL16618815 | 0.76 | EGFR (0.39) | ALDH1A1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |