Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618812 | 1.00 | EGFR (0.39) | EGFRALDH1A1GAAHTTKRAS | |
| SCHEMBL16619605 | 0.90 | SOS1 (0.47) | EGFRALDH1A1GAAHTTKRAS | |
| SCHEMBL16619606 | 0.90 | SOS1 (0.47) | EGFRALDH1A1GAAHTTKRAS | |
| SCHEMBL16619574 | 0.86 | EGFR (0.39) | EGFRALDH1A1GAAHTTKRAS | |
| SCHEMBL16619572 | 0.86 | EGFR (0.39) | EGFRALDH1A1GAAHTTKRAS | |
| SCHEMBL16618856 | 0.86 | EGFR (0.42) | EGFRALDH1A1GAAKRASSOS1 | |
| SCHEMBL16618852 | 0.86 | EGFR (0.42) | EGFRALDH1A1GAAKRASSOS1 | |
| SCHEMBL16619217 | 0.83 | ALDH1A1 (0.49) | EGFRALDH1A1GAAHTTCRHBP | |
| SCHEMBL16619219 | 0.83 | ALDH1A1 (0.49) | EGFRALDH1A1GAAHTTCRHBP | |
| SCHEMBL16619416 | 0.80 | KDM4E (0.46) | ALDH1A1GAAHTTHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |