Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619569 | 0.81 | F2 (0.43) | ALDH1A1KDM4EUSP2POLBF2 | |
| SCHEMBL4033816 | 0.79 | CYP3A4 (0.42) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL15650612 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL15652028 | 0.79 | ALOX5AP (0.44) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL29171366 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL4670678 | 0.78 | NCEH1 (0.38) | ALDH1A1KDM4EUSP2POLBPLAU | |
| SCHEMBL15651313 | 0.77 | MAPT (0.62) | ALDH1A1KDM4EUSP2GAAMAPT | |
| SCHEMBL15653165 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL12833000 | 0.76 | KDM4E (0.35) | ALDH1A1KDM4EUSP2POLBALOX5AP | |
| SCHEMBL2912192 | 0.76 | MAPT (0.59) | ALDH1A1KDM4EUSP2POLBMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |