Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720318 | 0.83 | F2 (0.50) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL16619241 | 0.81 | ALDH1A1 (0.40) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL4465791 | 0.80 | F2 (0.47) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL11133841 | 0.78 | KDM4E (0.54) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL8183595 | 0.76 | F2 (0.44) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL11708727 | 0.76 | F2 (0.47) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL28412157 | 0.75 | TSHR (0.53) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL16619494 | 0.75 | MAPT (0.42) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL22498562 | 0.75 | L3MBTL1 (0.48) | F2PLAUST14ALDH1A1MAPT | |
| SCHEMBL20374569 | 0.74 | CYP1A2 (0.69) | F2PLAUST14ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |