Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RHOA | P61586 | 2/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619312 | 1.00 | PTGES (0.52) | PTGESMAPTRHOAEIF2AK2CSNK2A2 | |
| SCHEMBL16619311 | 1.00 | PTGES (0.52) | PTGESMAPTRHOAEIF2AK2CSNK2A2 | |
| SCHEMBL9386732 | 0.88 | PTGES (0.55) | PTGESMAPTRHOAEIF2AK2CSNK2A2 | |
| SCHEMBL9551038 | 0.88 | PTGES (0.55) | PTGESMAPTRHOAEIF2AK2CSNK2A2 | |
| SCHEMBL1174503 | 0.83 | MAPT (0.64) | PTGESMAPTRHOANPSR1KMT2A | |
| SCHEMBL3602553 | 0.83 | MAPT (0.64) | PTGESMAPTRHOANPSR1KMT2A | |
| SCHEMBL989659 | 0.83 | MAPT (0.64) | PTGESMAPTRHOANPSR1KMT2A | |
| SCHEMBL4613192 | 0.81 | MIF (0.59) | PTGESMAPTRHOANPSR1KMT2A | |
| SCHEMBL7134052 | 0.81 | PTGES (0.59) | PTGESMAPTRHOANPSR1KMT2A | |
| SCHEMBL4613190 | 0.81 | MIF (0.59) | PTGESMAPTRHOANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |