Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 5/20 | 0.43 |
| ▸ | GABRD | O14764 | 5/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.43 |
| ▸ | GABRE | P78334 | 5/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648 | 0.87 | TNKS (0.50) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL11500 | 0.87 | TNKS (0.50) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL15528315 | 0.87 | TNKS (0.50) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL8656 | 0.86 | GABRP (0.49) | CA1CA2GABRPGABRDGABRA1 | |
| SCHEMBL15528300 | 0.85 | GABRP (0.50) | TNKSCA1CA2PIK3CDPIK3CG | |
| SCHEMBL9282 | 0.84 | TNKS (0.52) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL8910 | 0.84 | TNKS (0.52) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL15528175 | 0.81 | TNKS (0.44) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL15528285 | 0.78 | GABRP (0.51) | TNKSCA1CA2PIK3CDPIK3R2 | |
| SCHEMBL8932 | 0.78 | GABRP (0.51) | TNKSCA1CA2PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051241-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2015-04-09 | — | — | WO | disclosed |