Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KRAS | P01116 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619605 | 1.00 | SOS1 (0.47) | SOS1EGFRKRASPOLBALDH1A1 | |
| SCHEMBL16618812 | 0.90 | EGFR (0.39) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16618815 | 0.90 | EGFR (0.39) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16619574 | 0.87 | EGFR (0.39) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16619572 | 0.87 | EGFR (0.39) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16619219 | 0.87 | ALDH1A1 (0.49) | EGFRPOLBALDH1A1GAAHTT | |
| SCHEMBL16619217 | 0.87 | ALDH1A1 (0.49) | EGFRPOLBALDH1A1GAAHTT | |
| SCHEMBL16618740 | 0.84 | EGFR (0.51) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16618743 | 0.84 | EGFR (0.51) | SOS1EGFRKRASALDH1A1GAA | |
| SCHEMBL16619418 | 0.84 | KDM4E (0.46) | POLBALDH1A1GAAHTTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |