Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14776611 | 0.84 | VHL (0.44) | VHLHCAR2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL25602286 | 0.83 | POLB (0.43) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7450688 | 0.79 | LMNA (0.41) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL434029 | 0.78 | HCAR2 (0.52) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7463131 | 0.78 | LMNA (0.40) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14167211 | 0.77 | HCAR2 (0.46) | VHLHCAR2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7450681 | 0.74 | LMNA (0.40) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16477942 | 0.74 | VHL (0.39) | VHLHCAR2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15354785 | 0.74 | VHL (0.39) | VHLHCAR2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL16619623 | 0.73 | SMN1; SMN2 (0.43) | LMNAVHLHCAR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |