Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | VHL | P40337 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21877286 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1POLBLMNANPC1 | |
| SCHEMBL28921408 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1POLBLMNANPC1 | |
| SCHEMBL14776611 | 0.78 | VHL (0.44) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7450688 | 0.76 | LMNA (0.41) | SMN1; SMN2ALDH1A1POLBLMNANPC1 | |
| SCHEMBL18551330 | 0.75 | KMT2A (0.43) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL17755898 | 0.75 | VHL (0.42) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7463131 | 0.75 | LMNA (0.40) | SMN1; SMN2ALDH1A1POLBLMNANPC1 | |
| SCHEMBL16619625 | 0.73 | LMNA (0.43) | SMN1; SMN2ALDH1A1POLBLMNANPC1 | |
| SCHEMBL21877129 | 0.73 | CYP1A2 (0.41) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL21876986 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |