Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618967 | 0.85 | ENPP1 (0.34) | — | |
| SCHEMBL14756275 | 0.78 | EGFR (0.45) | ABCB1JAK3ABCG2EGFR | |
| SCHEMBL16619769 | 0.78 | FGFR1 (0.45) | EGFR | |
| SCHEMBL30878050 | 0.74 | CGAS (0.35) | ABCB1JAK3ABCG2EGFR | |
| SCHEMBL21404361 | 0.74 | CGAS (0.35) | ABCB1JAK3ABCG2EGFR | |
| SCHEMBL12496270 | 0.72 | EGFR (0.45) | ABCB1JAK3ABCG2EGFR | |
| SCHEMBL16618814 | 0.71 | CTSB (0.33) | EGFR | |
| SCHEMBL15009950 | 0.69 | TLR8 (0.41) | — | |
| SCHEMBL21050938 | 0.69 | KMT2A (0.39) | EGFR | |
| SCHEMBL15010142 | 0.69 | KDM4E (0.35) | SLC22A12JAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |