Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618705 | 0.88 | MAPT (0.34) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL16619235 | 0.88 | CTSB (0.32) | CTSB | |
| SCHEMBL15973592 | 0.82 | PDGFRB (0.40) | MAPTMEN1KMT2ALMNAEGFR | |
| SCHEMBL16618824 | 0.81 | S1PR4 (0.35) | MAPTRAB9AEGFRERBB2ALDH1A1 | |
| SCHEMBL26131542 | 0.77 | PDGFRB (0.43) | MAPTMEN1KMT2ALMNAEGFR | |
| SCHEMBL29970057 | 0.77 | PDGFRB (0.43) | MAPTMEN1KMT2ALMNAEGFR | |
| SCHEMBL16618907 | 0.76 | ENPP1 (0.31) | MAPTRAB9AEGFRERBB2 | |
| SCHEMBL16619572 | 0.75 | EGFR (0.39) | EGFRGAAHTTALDH1A1 | |
| SCHEMBL16619574 | 0.75 | EGFR (0.39) | EGFRGAAHTTALDH1A1 | |
| SCHEMBL16618826 | 0.75 | CYP1A2 (0.41) | CTSBMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |