SCHEMBL16620219

SCHEMBL16620219

CCCC(C#N)CN=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.39
MEN1 O00255 7/20 0.39
TAAR1 Q96RJ0 2/20 0.39
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA2 P00918 3/20 0.34
ALDH1A1 P00352 5/20 0.34
HPGD P15428 4/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
POLB P06746 2/20 0.34
USP2 O75604 1/20 0.34
CASP1 P29466 1/20 0.34
BRCA1 P38398 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
GRIN2D O15399 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17985143 1.00 KMT2A (0.39) KMT2AMEN1TAAR1LMNAL3MBTL1
SCHEMBL21957529 0.86 SMN1; SMN2 (0.43) KMT2AMEN1TAAR1CA2ALDH1A1
SCHEMBL21957527 0.86 SMN1; SMN2 (0.43) KMT2AMEN1TAAR1CA2ALDH1A1
SCHEMBL21957526 0.84 NPC1 (0.49) KMT2AMEN1LMNAALDH1A1HPGD
SCHEMBL21957528 0.84 NPC1 (0.49) KMT2AMEN1LMNAALDH1A1HPGD
SCHEMBL21957556 0.81 ALDH1A1 (0.34) LMNAL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL21957555 0.81 ALDH1A1 (0.34) LMNAL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL17985154 0.78 CA2 (0.41) KMT2AMEN1TAAR1LMNAL3MBTL1
SCHEMBL17985153 0.78 CA2 (0.41) KMT2AMEN1TAAR1LMNAL3MBTL1
SCHEMBL17985135 0.77 MEN1 (0.39) KMT2AMEN1TAAR1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052531-B1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORP (JP) 2024-07-24 EP disclosed
US-11066486-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2021-07-20 US disclosed
US-20200157253-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2020-05-21 US disclosed
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US disclosed
US-20160237179-A1 Polymers Functionalized With Imine Compounds Containing A Cyano Group BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
EP-3052531-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2016-08-10 EP disclosed
WO-2015050947-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-04-09 WO disclosed