SCHEMBL16620306

SCHEMBL16620306

Cc1ccccc1N=C1CCC(C#N)CC1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
HSD11B1 P28845 1/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
PAX8 Q06710 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TSHR P16473 2/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2C9 P11712 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16620210 0.91 ALDH1A1 (0.35) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL16620211 0.91 ALDH1A1 (0.35) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL16620334 0.82 ALDH1A1 (0.33) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL16620333 0.82 ALDH1A1 (0.33) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL8743963 0.80 USP2 (0.38) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL8743946 0.78 USP2 (0.37) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL8743999 0.78 USP2 (0.37) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL17985127 0.76 KDM4E (0.34) ALDH1A1KMT2AKDM4E
SCHEMBL8743997 0.75 USP2 (0.36) USP2HSD11B1LMNAALDH1A1TP53
SCHEMBL8744047 0.75 HSD11B1 (0.41) USP2HSD11B1LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066486-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2021-07-20 US disclosed
US-20200157253-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2020-05-21 US disclosed
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US disclosed
US-20160237179-A1 Polymers Functionalized With Imine Compounds Containing A Cyano Group BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
EP-3052531-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2016-08-10 EP disclosed
WO-2015050947-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-04-09 WO disclosed