Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595005 | 1.00 | MEN1 (0.31) | MEN1KMT2ANAAAL3MBTL1CTSL | |
| SCHEMBL16603743 | 0.90 | GAA (0.36) | NAAA | |
| SCHEMBL15529696 | 0.85 | NAAA (0.38) | NAAA | |
| SCHEMBL15366729 | 0.85 | NAAA (0.38) | NAAA | |
| SCHEMBL16594337 | 0.83 | — | — | |
| SCHEMBL16593841 | 0.83 | SHBG (0.31) | — | |
| SCHEMBL16603880 | 0.82 | SCN9A (0.36) | CTSSCTSK | |
| SCHEMBL15366699 | 0.82 | NAAA (0.38) | NAAA | |
| SCHEMBL15530051 | 0.82 | NAAA (0.38) | NAAA | |
| SCHEMBL15530464 | 0.81 | NAAA (0.38) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052491-A1 | USE OF MACROCYLIC PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-3052490-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050818-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015050819-A1 | USE OF MACROCYLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-04-09 | — | — | WO | disclosed |