Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.37 |
| ▸ | CDK9 | P50750 | 10/20 | 0.37 |
| ▸ | ELANE | P08246 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119494 | 0.91 | CDK2 (0.39) | CDK2CDK9ELANE | |
| SCHEMBL2153112 | 0.86 | CDK2 (0.36) | CDK2CDK9 | |
| SCHEMBL21300042 | 0.83 | KCNH2 (0.33) | KDM4ELMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL9610888 | 0.79 | CDK2 (0.39) | CDK2CDK9ELANEGAASMN1; SMN2 | |
| SCHEMBL12425338 | 0.79 | ALDH1A1 (0.34) | KDM4ELMNASMN1; SMN2NPSR1HDAC6 | |
| SCHEMBL2152745 | 0.78 | DAO (0.41) | ELANE | |
| SCHEMBL121954 | 0.78 | ALDH1A1 (0.43) | CDK2CDK9KDM4EGAASMN1; SMN2 | |
| SCHEMBL18231808 | 0.78 | CDK2 (0.36) | CDK2CDK9 | |
| SCHEMBL16622004 | 0.77 | DAO (0.37) | CDK2 | |
| SCHEMBL2153234 | 0.77 | CDK2 (0.36) | CDK2CDK9HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120701-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-3120701-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-2369921-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2369935-B1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20100144803-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | CORTEVA AGRISCIENCE LLC | 2010-06-10 | — | — | US | disclosed |
| US-20100144803-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | CORTEVA AGRISCIENCE LLC | 2010-06-10 | — | — | US | disclosed |
| US-20100144794-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | CORTEVA AGRISCIENCE LLC | 2010-06-10 | — | — | US | disclosed |
| US-7687634-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687634-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-03-30 | — | — | US | disclosed |
| WO-2009014891-A2 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144794-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | PRDX6, DDT, HDHD5 | CDK2 4262/4885CDK9 4537/4885ELANE 2039/4885 |
| US-20090023782-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | CDK2 2195/4885CDK9 1056/4885ELANE 4647/4885 |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | CDK2 4506/4885CDK9 4646/4885ELANE 1800/4885 |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | NPEPPS, PRDX6, HDHD5 | CDK2 4345/4885CDK9 4545/4885ELANE 2120/4885 |
| US-20100144803-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | PRDX6, DDT, HDHD5 | CDK2 4262/4885CDK9 4537/4885ELANE 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.