Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125736 | 1.00 | ACHE (0.44) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1662213 | 1.00 | ACHE (0.44) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1662432 | 0.95 | ACHE (0.40) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1662438 | 0.91 | PTPRF (0.38) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1664516 | 0.88 | EGFR (0.45) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1664515 | 0.88 | EGFR (0.45) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1659912 | 0.83 | PTPRF (0.60) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1659911 | 0.83 | PTPRF (0.60) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL15240243 | 0.83 | PTPRF (0.60) | ACHEHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL1662257 | 0.80 | PTPRF (0.42) | ACHEHSD17B10ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640423-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | Ischemix LLC (US) | 2013-09-25 | — | — | EP | claimed |
| WO-2012067947-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2012-05-24 | — | — | WO | claimed |
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | claimed |
| EP-2640423-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | Ischemix LLC (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067947-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |