Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | PTPRF | P10586 | 8/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664515 | 1.00 | EGFR (0.45) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL1662214 | 0.88 | ACHE (0.44) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL1662213 | 0.88 | ACHE (0.44) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL6125736 | 0.88 | ACHE (0.44) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL1657891 | 0.84 | PTPRF (0.59) | PTPRFPTPN2PTPN1BCHEACHE | |
| SCHEMBL1657894 | 0.84 | PTPRF (0.59) | PTPRFPTPN2PTPN1BCHEACHE | |
| SCHEMBL1662432 | 0.84 | ACHE (0.40) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL1662438 | 0.82 | PTPRF (0.38) | EGFRNOX4PTPRFPTPN2PTPN1 | |
| SCHEMBL1664293 | 0.81 | BCHE (0.42) | PTPRFPTPN2PTPN1BCHEACHE | |
| SCHEMBL1657906 | 0.77 | PTPRF (0.47) | PTPRFPTPN2PTPN1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |