Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.90 |
| ▸ | PLAU | P00749 | 1/20 | 0.73 |
| ▸ | PLAUR | Q03405 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284987 | 0.94 | NTRK1 (1.00) | NTRK1PLAUPLAURMAPTPOLB | |
| SCHEMBL13284995 | 0.92 | NTRK1 (0.86) | NTRK1PLAUPLAURMAPTPOLB | |
| SCHEMBL16037129 | 0.87 | NTRK1 (0.86) | NTRK1PLAUPLAURMAPTPOLB | |
| SCHEMBL2480771 | 0.86 | NTRK1 (0.84) | NTRK1PLAUPLAURMAPTPOLB | |
| SCHEMBL16978026 | 0.85 | NTRK1 (0.76) | NTRK1PLAUPLAURMAPTPOLB | |
| SCHEMBL12698762 | 0.85 | PLAUR (0.86) | NTRK1PLAUPLAURMAPTEHMT2 | |
| SCHEMBL17874500 | 0.85 | PLAU (0.81) | NTRK1PLAUPLAURMAPTEHMT2 | |
| SCHEMBL30019219 | 0.84 | PLAU (1.00) | NTRK1PLAUPLAURMAPTEHMT2 | |
| SCHEMBL12499325 | 0.84 | PLAU (1.00) | NTRK1PLAUPLAURMAPTEHMT2 | |
| SCHEMBL13284981 | 0.84 | NTRK1 (0.81) | NTRK1PLAUPLAURMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999992-B2 | Crystalline forms of tryosine kinase inhibitors and their salts | VM PHARMA LLC (US) | 2015-04-07 | — | — | US | disclosed |